When the octagon doors close at Crypto.com Arena in Los Angeles on September 19, 2026, the UFC flyweight division will resolve a lingering question mark that has hung over the 125-pound weight class for nine months. UFC 331 brings 24-year-old champion Joshua Van and former titleholder Alexandre Pantoja face-to-face in a high-stakes rematch to determine the undisputed ruler of the division.

Unfinished Business at 125 Pounds

The rivalry between Van and Pantoja traces back to UFC 323 in December 2025, where their initial championship encounter ended after just 26 seconds. Pantoja suffered a dislocated elbow when Van fell and landed directly on him during an early exchange, abruptly ending the Brazilian veteran's reign. While the official result crowned Van as the champion, the injury-enforced stoppage left Pantoja—nicknamed The Cannibal—harboring intense frustration over how his championship run ended.

Prior to that sudden halt, the 36-year-old Pantoja had assembled an eight-fight winning streak that solidified his standing at the top of the weight class. His championship resume features victories over elite flyweights including Brandon Moreno, Brandon Royval, Steve Erceg, Kai Asakura, and Kai Kara-France. Entering the September 19 rematch, Pantoja aims to join Moreno and Deiveson Figueiredo as only the third fighter in UFC flyweight history to regain the 125-pound title after losing it.

Advertisement

Meanwhile, Myanmar native Van proved his initial title capture was no fluke during his solitary title defense in May. Showing off quick speed and sharp, aggressive volume striking, the 24-year-old defeated Japanese phenom Tatsuro Taira via final-round stoppage in an instant classic that earned wide acclaim across combat sports.

Joshua Van and Alexandre Pantoja facing off during UFC 331 promotional events
Fighter face-offs and press conference tensions have ramped up ahead of the September 19 championship rematch.Image source: cagesidepress.com

Heavy Heat and Press Conference Tensions

The build-up to UFC 331 in Los Angeles has featured noticeable animosity between the two 5-foot-5 competitors. During a joint promotional press conference in Philadelphia prior to UFC 330, Van insisted that the result of their first fight was inevitable regardless of Pantoja's arm injury.

blockquote>

Had that not happened, I would still whup his ass that day. September 19 is just another opportunity for me to whup his ass again.

Pantoja responded aggressively, warning the young champion about respect while security stepped in to maintain order between the two men.

blockquote>

First, I think he needs to wash his mouth. I respect where I’m from, I’m from Brazil. In Brazil, you need to take care about what you talk. If you don’t, maybe you lose your teeth.

Lightweight Co-Main Event: Tsarukyan's High-Stakes Pivot Against Ruffy

In the co-main event at Crypto.com Arena, second-ranked lightweight contender Arman Tsarukyan returns from an 11-month layoff to face 10th-ranked Brazilian striker Mauricio Ruffy. The 29-year-old Armenian lightweight had originally agreed to a five-round contender clash against former champion Charles Oliveira in a rematch of their 2024 bout. However, plans changed following the sudden passing of Oliveira's friend and teammate, UFC flyweight Allan Nascimento, who died at age 34 from an apparent heart attack.

Arman Tsarukyan during UFC competition coverage by The Independent
Arman Tsarukyan takes on Mauricio Ruffy in a high-stakes lightweight co-main event at Crypto.com Arena.Image source: independent.co.uk

Already deep into his training camp in Armenia, Tsarukyan chose to take the matchup against the 30-year-old Ruffy rather than stay on the sidelines. His urgency comes after a rocky stretch with UFC management following his late withdrawal on one day's notice from a planned championship fight against Islam Makhachev in January 2025. UFC CEO Dana White openly noted earlier this year that he was not thrilled with Tsarukyan for multiple reasons. Now, Tsarukyan views a decisive win over Ruffy as his mandatory ticket back to a lightweight title fight.

Evidence-Led Forecast: UFC 331 Main Event Decisive Matchup and Division Impact

Heading into September 19, the flyweight main event between Joshua Van and Alexandre Pantoja turns on a clear tactical contrast: Van's high-volume inside boxing speed against Pantoja's persistent grappling pressure and aggressive scramble mechanics.

  • Decisive Matchup Driver: Van's ability to maintain lateral range and deploy the sharp combination punching that disarmed Tatsuro Taira in May will be crucial in neutralizing Pantoja's pursuit of body locks and mat returns.
  • Primary Uncertainty: How effectively Pantoja has recovered from his elbow dislocation, and whether his 36-year-old frame can match the relentless pace and volume output of a champion 12 years his junior over five rounds.

Sources

These sources formed the evidence pack for this article. Links open the original publisher; inclusion does not imply endorsement.

  1. techradar.com original
  2. fightersonly.com original
  3. cagesidepress.com original
  4. independent.co.uk original